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Biopolymers for Biomedical Applications

1. Aufl.

von: Annu
216,99 €
Verlag:	Wiley
Format:	PDF
Veröffentl.:	22.03.2024
ISBN/EAN:	9781119865445
Sprache:	englisch
Anzahl Seiten:	560

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Titelbeschreibung

Biopolymers for Biomedical Applications The twenty chapters written by experts in the field of biopolymers and biomedical engineering, provide a complete resource that systematically discusses the most widely used biopolymers and their biomedical applications, and presents all the important research and developments that have occurred in the field. In recent decades, significant progress has been made in polymer science for biomedical applications. The use of biopolymers specifically attracted the focus on the development of therapeutic polymeric systems. The exclusive features of biopolymers, such as biodegradability and biocompatibility make them highly sought after, and major research conducted with them has resulted in various therapeutic systems. However, until now only a few showed a potential to be appropriate for human use. Each chapter covers a single biopolymer, its properties, and biomedical applications. The chapters are arranged systematically, with the most common biopolymers discussed early in the book to give more insight into the field. Further, a specific chapter is dedicated to the application of biopolymers for wound healing. Later, specific chapters are dedicated to the application of bioplastics and biopolymers for the development of medical devices and biosensors, respectively. Additionally, a chapter is dedicated to the application of biopolymers in the field of dentistry, with a special focus on their risk to human health. Keeping in mind recent advanced technologies, a chapter is dedicated solely to the latest progress of biopolymers in 3D and 4D printing for biomedical applications. The final chapter comprehensively explains the future perspectives of biopolymers in the biomedical field. Audience The book is a reference source for scientists, research scholars, chemical and polymer engineers, biologists, biotechnologists, polymer technologists, industrialists, health experts, and policymakers.

Inhaltsverzeichnis

Preface xix 1 Introduction to Biopolymers 1 Gurleen Kaur, Rajinder Kaur and Sukhminderjit Kaur 1.1 Introduction 1 1.2 Classification of Biopolymers 3 1.3 Commonly Used Biopolymers 3 1.4 Preparation of Biopolymers 7 1.5 Commercially Available Biopolymers 9 1.6 Biomedical Applications of Biopolymers 11 1.7 Conclusion 20 2 Biomedical Applications of Chitosan and Its Derivatives 25 Hitesh Malhotra and Rupesh K. Gautam 2.1 Introduction 25 2.2 Characteristics of Chitosan 27 2.3 Application of Chitosan in Biomedicine 30 2.4 Conclusion 43 3 Biomedical Applications of Alginates 53 Payal Kesharwani, Swapnil Sharma, Vishal Chaudhary, Rajat Goyal and Rupesh K. Gautam 3.1 Introduction 54 3.2 Structure and Characterization 56 3.3 General Properties of Alginates 57 3.4 Alginate and Alginate Composites as a Drug Delivery System 60 3.5 Biomedical Application of Alginates 62 3.6 Conclusion and Future Prospective of Alginates 74 4 Biomedical Applications of Cellulose 87 Abhishek Kanugo, Pallavi Chaudhari and Rupesh K. Gautam 4.1 Introduction 88 4.2 Structure and Properties of Cellulose 88 4.3 Types of Cellulose 90 4.4 Applications of Cellulose 90 4.5 Applications in Ocular Systems 108 4.6 Applications in Skeletal Systems 111 4.7 Miscellaneous 114 4.8 Conclusion 114 5 Biomedical Applications of Starch 129 Daud Hussain, Suhail Ayoub Khan, Annu and Tabrez Alam Khan 5.1 Introduction 130 5.2 Structure and Properties of Starch 132 5.3 Modified Starches 133 5.4 Pharmaceutical and Biomedical Applications 137 5.5 Starch for Novel Drug Delivery 138 5.6 Encapsulants 139 5.7 Micro/Nanoparticle Hydrogels 140 5.8 Scaffolds for Wound Healing 140 5.9 Conclusions 142 6 Biomedical Applications of Carrageenan 151 Hitesh Chopra and Rupesh K. Gautam 6.1 Introduction 151 6.2 Structure of Carrageenan 152 6.3 Biomedical Applications 153 6.4 Toxicity 163 6.5 Challenges, Conclusion, and Future Trends 164 7 Biomedical Applications of Gums 175 Suhail Ahmed, Nagender Singh and Annu 7.1 Introduction 175 7.2 Physicochemical Properties of Gums 176 7.3 Biomedical Applications of Guar Gum 180 7.4 Biomedical Applications of Xanthan Gum 181 7.5 Biomedical Applications of Gum Arabic 183 7.6 Biomedical Applications of Gum Tragacanth 185 7.7 Conclusion and Future Perspective 187 8 Biomedical Applications of Cyclodextrin 199 Iftkhar Ahmad, Abu Taha, Annu, Athar Adil Hashmi and Saiqa Ikram 8.1 Introduction 200 8.2 Biomedical Applications of Cyclodextrin 201 8.3 Future Prospects 212 8.4 Conclusion 213 9 Biomedical Applications of Dextran 219 Sonia Sharma and Jagadeesh Chandra Bose K 9.1 Introduction 219 9.2 Biomedical Applications of Dextran 221 9.3 Conclusion 238 10 Biomedical Applications of Pullulan 253 Sudipta Roy, Swaraj Biswas, Soumalya Chakraborty, Sanjay Kumar Das and Richita Mondal 10.1 Introduction 254 10.2 Sources of Pullulan 255 10.3 Properties of Pullulan 256 10.4 Biomedical Applications 257 10.5 Conclusion 272 11 Biomedical Applications of Collagen/Gelatin 287 Jyoti Sarwan, Jasjeet Narang, Anushka Kumari, Monika Devi, Nazim Uddin, Savita Sharma and Jagadeesh Chandra Bose K 11.1 Introduction 287 11.2 Structure of Collagen 289 11.3 Modification of Collagen 293 11.4 Biomedical Applications of Collagen/Gelatin 296 11.5 Conclusion 307 12 Biomedical Applications of Pectin 315 Heenu Sharma, Jyoti Sarwan, Mariyam Chaudhary,Riya Chugh and Jagadeesh Chandra Bose K 12.1 Introduction 315 12.2 Biomedical Applications of Pectin 317 13 Biomedical Applications of Lignin Derived from Bio-Waste Materials 333 Nancy George, Anshika Adlakha, Mridula, Pragati Gupta and Abhrajit Debroy 13.1 Introduction 334 13.2 Structure of Lignin 335 13.3 Sources of Lignin 337 13.4 Extraction of Lignin 341 13.5 Properties of Lignin for Biomedical Applications 346 13.6 Biomedical Applications of Lignin 349 13.7 Therapeutic Applications of Lignin 354 13.8 Feasibilities, Challenges, and Prospects 360 13.9 Conclusion 361 14 Biomedical Applications of Polycaprolactone 373 Anindita Ray (Chakravarti) and Annu 14.1 Introduction 373 14.2 Structure of PCL 374 14.3 Characteristic Properties of PCL 375 14.4 Synthesis 376 14.5 Modifications of PCL 378 14.6 Biomedical Applications of PCL 380 14.7 Current Challenges 386 14.8 Conclusion 386 15 Biopolymers for Wound Healing Applications 393 Hitesh Chopra 15.1 Introduction 393 15.2 Wound Healing Stages 394 15.3 Biopolymers 396 15.4 Conclusion and Future Directions 407 16 Bioplastics in Medical Devices 417 Reshma Soman, Divyanshi Mangla and Annu 16.1 Introduction 417 16.2 Plastics and Their Environmental Concern 418 16.3 Need for Bioplastics 420 16.4 Bioplastics 421 16.5 Biomedical Applications of Polylactic Acid 422 16.6 Biomedical Applications of PLGA 426 16.7 PLGA in Bone Tissue Engineering 426 16.8 Biomedical Applications of Poly(ԑ-caprolactone) 429 16.9 Conclusion 432 17 Biopolymers in Biosensors 439 Jincymol Kappen, Feba Anna John and Ajith James Jose 17.1 What are Biosensors? 439 17.2 Biopolymers 440 17.3 Conclusion 450 18 Biopolymers in Dentistry: A Risk Assessment on Human Health 459 Stanley C. Onwubu, Chibuzor Stellamaria Okonkwo, Mokgadi Ursula Makgobole and Phumlane Selby Mdluli 18.1 Introduction 459 18.2 Biopolymers in Healthcare 461 18.3 Classification of Biopolymers 461 18.4 Biopolymers Used in Dentistry 462 18.5 Risk Assessment of Biopolymers in Dentistry 467 18.6 Discussion 469 18.7 Conclusion 471 19 Progress of Biopolymers in 3D and 4D Printing for Biomedical Applications 479 Randeep Singh and Young-Ho Ahn 19.1 Introduction 480 19.2 Overview on 3D and 4D Printing Technologies 480 19.3 4D Printing 483 19.4 Overview on Biopolymers for 3D and 4D Printing 485 19.5 Stimuli for 4D Transformation 487 19.6 Biopolymers Used for 3D and 4D Printing 490 19.7 Biomedical Applications of Biopolymers Based 3D- and 4D-Printed Bioconstructs 491 19.8 Other Applications 496 19.9 Future Perspectives and Conclusion 498 20 Future Perspectives of Biopolymers for Biomedical Applications 509 Hitesh Chopra, Shivani Sharma, Mohd Shabbir, Annu and Dong-Kil Shin 20.1 Introduction 510 20.2 Role of Biopolymers in 3D Printing 511 20.3 Biopolymers in Recent Intelligent Biomedical Systems 515 20.4 Critical Aspects of Biopolymers in Biomedical Applications 521 20.5 Conclusion and Future Perspective 521 References 522 Index 531

Autorenportrait

Dr. Annu is an assistant professor in the Department of Mechanical Engineering, Yeungnam University, Republic of Korea. Besides, she is an honorary assistant professor in the Department of Science and Engineering in Novel Global Community Education Foundation, Australia. She obtained her graduation and post-graduation degree in chemistry from the University of Allahabad and a doctoral degree in chemistry from Jamia Millia Islamia, New Delhi. She has gained further research experience as research associate from the Indian Institute of Technology Delhi. She has published several scientific research articles in international peer-reviewed journals and many book chapters with publishers of international repute. Her research interests include fabrication and modification of sustainable bionanocomposites, biomaterials, green synthesis of nanoparticles, hybrid nanomaterials, modification in biopolymers and composite nanomaterials for their applications in biomedical, food packaging, nutraceuticals, energy storage devices, biosensors, textiles and environment sustainability.

Back cover copy

The twenty chapters written by experts in the field of biopolymers and biomedical engineering, provide a complete resource that systematically discusses the most widely used biopolymers and their biomedical applications, and presents all the important research and developments that have occurred in the field. In recent decades, significant progress has been made in polymer science for biomedical applications. The use of biopolymers specifically attracted the focus on the development of therapeutic polymeric systems. The exclusive features of biopolymers, such as biodegradability and biocompatibility make them highly sought after, and major research conducted with them has resulted in various therapeutic systems. However, until now only a few showed a potential to be appropriate for human use. Each chapter covers a single biopolymer, its properties, and biomedical applications. The chapters are arranged systematically, with the most common biopolymers discussed early in the book to give more insight into the field. Further, a specific chapter is dedicated to the application of biopolymers for wound healing. Later, specific chapters are dedicated to the application of bioplastics and biopolymers for the development of medical devices and biosensors, respectively. Additionally, a chapter is dedicated to the application of biopolymers in the field of dentistry, with a special focus on their risk to human health. Keeping in mind recent advanced technologies, a chapter is dedicated solely to the latest progress of biopolymers in 3D and 4D printing for biomedical applications. The final chapter comprehensively explains the future perspectives of biopolymers in the biomedical field. Audience The book is a reference source for scientists, research scholars, chemical and polymer engineers, biologists, biotechnologists, polymer technologists, industrialists, health experts, and policymakers.